Phyto-cannabinoids and Terpenoids May Decrease Inflammation
“…a wealth of information also indicates that these drugs [phyto-cannabinoids] have immunosuppressive and anti-inflammatory properties; therefore, on the basis of this mode of action, the therapeutic usefulness of these drugs in chronic inflammatory diseases is now being reassessed.”
Klein, Thomas W. (2005). Cannabinoid-Based Drugs as Anti-Inflammatory Therapeutics.
Source: Nature Reviews Immunology
Anti-Inflammatory Benefits of Cannabidiol
“This review discusses recent studies suggesting that cannabidiol may have utility in treating a number of human diseases and disorders now known to involve activation of the immune system and associated oxidative stress, as a contributor to their etiology and progression. These include rheumatoid arthritis, types 1 and 2 diabetes, atherosclerosis, Alzheimer disease, hypertension, the metabolic syndrome, ischemia-reperfusion injury, depression, and neuropathic pain.”
Booz, George W. (2011) Cannabidiol as an Emergent Therapeutic Strategy for Lessening the Impact of Inflammation on Oxidative Stress.
Source: Free Radical Biology and Medicine
Study Finds Cannabinoids Produce Anti-Inflammatory Responses in Autoimmune Disorders
“Cannabinoids suppress inflammatory response and subsequently attenuate disease symptoms…Cannabinoids have been tested in several experimental models of autoimmune disorders such as multiple sclerosis, rheumatoid arthritis, colitis and hepatitis and have been shown to protect the host from the pathogenesis through induction of multiple anti-inflammatory pathways…Cannabinoids may also be beneficial in certain types of cancers that are triggered by chronic inflammation. In such instances, cannabinoids can either directly inhibit tumor growth or suppress inflammation and tumor angiogenesis.”
Nagarkatti, Prakash, et al. (2009). Cannabinoids as Novel Anti-Inflammatory Drugs.
Source: Future Medicinal Chemistry
Cannabinoids Suppress Inflammatory & Neuropathic Pain in Study
“…systemic and intrathecal administration of cannabidiol (CBD)… and its modified derivatives significantly suppress chronic inflammatory and neuropathic pain without causing apparent analgesic tolerance.”
Xiong, W., et al. (2012). Cannabinoids Suppress Inflammatory and Neuropathic Pain by Targeting a3 Glycine Receptors.
Source: Journal of Experimental Medicine